Motorists travelling around Deepdale on Saturday will need to deal with limited access during PNE match.
North End will be hosting Sheffield Wednesday, who have sold a large number of tickets for the weekend clash.
Due to the number of people travelling to the game, including the number of coaches that will be used by away fans, some roads have been restricted.
Lowthorpe Road, Moor Park Avenue and Bill Shankley Crescent will all be affected by restrictions that will be in place from 1pm to 6pm.
In a letter to residents, Lancashire Police have said, ‘I hope that these arrangements do not affect access to your property unduly.
‘However, I would ask that careful consideration is given to travel arrangements to and from your property within the affected times.
‘We understand the inconvenience that this causes to residents and we will of course make every effort to open the roads as quickly as possible once it is safe to do so.’